GHK-CU · 50 mg

from US$80.00

GHK-CU is a copper-binding peptide studied for collagen synthesis, skin biology and tissue remodelling.

Complimentary BAC water with every order.

Format:
Vial:

GHK-CU is a copper-binding peptide studied for collagen synthesis, skin biology and tissue remodelling.

Complimentary BAC water with every order.

Packaging & supply options

Your format, your way.

The same research peptide, with a choice of accessories and supply formats. Here’s what each option includes.

BAC water

Vial kit

Lyophilised peptide vial with separately packaged, complimentary BAC water.

BAC water + syringes

Syringe kit

Lyophilised peptide vial, BAC water and syringes.

BAC water + pen

Injection pen kit

Lyophilised peptide vial, BAC water and an injection pen.

Pen + pen needles

Reconstituted pen

VIETNAM ONLY

Peptide solution supplied in a pen at the stated concentration, with pen needles.

For laboratory research only. Not for human or veterinary use.

Everform Pharma · Compound profile

GHK-CU.
The science beneath the surface.

A closer look at copper-peptide signalling, collagen research and the biology of tissue remodelling.

Interwoven ivory ribbons and copper strands beside emerald glass on sunlit travertine, symbolising skin structure and tissue-matrix research.
Conceptual illustration of skin structure and tissue-matrix research.

What is GHK-CU?

GHK-CU is the copper complex of glycyl-L-histidyl-L-lysine: a short peptide made from three amino acids. GHK was isolated from human plasma and has an affinity for copper ions. Its copper-bound form is studied for its effects on connective-tissue biology. [1]

At the centre of that interest is the extracellular matrix — the network surrounding cells that gives tissues structure. Understanding how that network is produced and remodelled helps explain GHK-CU’s place in skin and repair research.

How does GHK-CU work?

Fibroblasts are cells involved in building connective tissue. In culture experiments, GHK-CU stimulated collagen synthesis, making fibroblast activity an important starting point for studying its biological effects. [1]

Remodelling also involves breaking down and reorganising existing material. A separate fibroblast study found changes in matrix metalloproteinase-2 and its tissue inhibitors, TIMP-1 and TIMP-2. This suggests a more complex research story than simply increasing collagen production. [3]

MATRIX PRODUCTION

Exploring how fibroblasts produce collagen and other connective-tissue components.

MATRIX REMODELLING

Investigating the enzymes and inhibitors involved in reorganising the tissue environment.

Main research areas

GHK-CU brings together several related questions about skin structure, connective tissue and repair.

Research areaWhat researchers examine
Collagen biologyCollagen synthesis by fibroblasts in laboratory cultures. [1]
Tissue repairCollagen and other extracellular-matrix components in experimental rat wounds. [2]
Matrix turnoverEnzymes and inhibitors involved in tissue remodelling in fibroblast cultures. [3]
Skin appearanceRedness, wrinkles, skin quality and satisfaction in a small human study of topical products after laser resurfacing. [4]

The study model and formulation matter: cell, animal and topical human findings answer different questions.

What published findings show

Cell studies: Maquart and colleagues reported increased collagen synthesis in fibroblast cultures. Later work by Siméon and colleagues explored enzymes and inhibitors involved in matrix turnover. Together, these studies provide a foundation for investigating connective-tissue remodelling. [1] [3]

Animal studies: In an experimental rat wound model, GHK-CU increased the accumulation of collagen and other matrix components. This was a controlled animal experiment, rather than a demonstration of faster healing in people. [2]

Human topical research: In a randomised post-laser study completed by 13 participants, the GHK-CU skincare group reported greater satisfaction. However, blinded and computer-based assessments did not find significant between-group improvements in redness, wrinkles or overall skin quality. [4]

Research on a topical skincare formulation does not establish the effects of a research vial or pen. Formulation, route and study population should remain part of any comparison.

The most useful way to explore GHK-CU is to connect each finding to the exact question studied: collagen production, tissue remodelling or a defined skin outcome.

The Everform product, at a glance

CompoundGHK-CU

Labelled vial amount50 mg

Base formatLyophilised peptide powder

Supply optionsSee the format guide above

Everform Pharma is based in Da Nang, Vietnam. Use the product selector to choose an available supply format. Complimentary BAC water is included with every order.

Explore Your format, your way →

Check the label for the full REF, expiry date and storage conditions. The security sticker on the transport package repeats the product identifier and should match the vial or pen inside. Match the full REF to the relevant documentation.

Identity, chromatographic purity and measured peptide content answer different questions on a COA. A purity percentage alone does not confirm the amount of peptide per vial.

Explore our label and COA guide →

Common questions

What does the copper component mean?

GHK is the three-amino-acid peptide; GHK-CU identifies its copper complex. Check that the compound named in a study matches the product being discussed. [1]

Is GHK-CU the same as AHK-Cu in hair research?

No. AHK-Cu contains alanine rather than glycine as its first amino acid. A frequently cited study of isolated human hair follicles tested AHK-Cu, so its findings should not be presented as a GHK-CU hair-growth result. [5]

Does “50 mg” describe a dose?

No. Here, 50 mg is the labelled amount of product in the vial. It is not a recommended dose or an administration instruction.

Is this equivalent to a finished skincare serum?

No. A lyophilised research product is different from a formulated topical cosmetic. Results from a particular serum or cream cannot automatically be transferred to a vial or pen.

Where should I check storage and identification?

Follow the storage conditions on your actual label. Check that the package security sticker matches the vial or pen, and use the full REF when requesting the matching documentation.

References

[1] Maquart et al. Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+. FEBS Letters, 1988.

[2] Maquart et al. In vivo stimulation of connective tissue accumulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ in rat experimental wounds. Journal of Clinical Investigation, 1993.

[3] Siméon et al. The tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ stimulates matrix metalloproteinase-2 expression by fibroblast cultures. Life Sciences, 2000.

[4] Miller et al. Effects of topical copper tripeptide complex on CO2 laser-resurfaced skin. Archives of Facial Plastic Surgery, 2006.

[5] Pyo et al. The effect of tripeptide-copper complex on human hair growth in vitro. Archives of Pharmacal Research, 2007. This study examined AHK-Cu.

Everform Pharma · Da Nang, Vietnam
Educational product information.
For laboratory research only.
Not for human or veterinary use.